Teixobactin a Promising Breakthrough But Still A Long Way Off

The discovery of teixobactin is a significant medical development but it could be years before it is available on the market.
NPS MedicineWise CEO Lynn Weekes warns that despite this major breakthrough, antibiotic resistance in Australia remains a serious health problem we all need to work to address.
“While the discovery of teixobactin is a promising breakthrough, actually bringing this new antibiotic to market will be a very lengthy process as it undergoes further studies and then testing in humans,” says Dr Weekes.
“We cannot afford to become complacent about the very real and immediate issue of antibiotic resistance. We risk losing the effect of existing antibiotics in the short term if the high rate of antibiotic use continues in Australia,” says Dr Weekes.
 
“Teixobactin is not a ‘quick fix’ and won’t provide defence against all bacteria. For example, it is not effective against any bacteria which have an outer membrane, known as ‘gram negative’ bacteria, such as E. coli. Multidrug resistant E. coli in urinary tract infections (UTIs) is present in Australia. E. coli now displays resistance rates to over 50% of commonly used antibiotics, and some strains have acquired resistance to more than three antibiotics.”
 
Australia has one of the highest rates of antibiotic use in the world with more than 24 million antibiotic prescriptions written every year. Australia sits well above the OECD average in relation to antibiotic use. To reduce our overuse the entire Australian community has a part to play.
 
NPS MedicineWise is part way through a five-year campaign to reduce inappropriate antibiotic prescribing in Australia by 25 per cent. The campaign encourages all Australians to be responsible with antibiotics and join the fight against antibiotic resistance.
 
“There are simple steps that health professionals and individuals can take to ensure they use antibiotics judiciously and appropriately. For health professionals this means adhering to best practice prescribing guidelines, and for the community it is important not to pressure your doctor for antibiotics when you have a cold or flu because these are not bacterial infections,” says Dr Weekes.
 
“The more antibiotics are used, the more chances bacteria have to become resistant to them. This can then make bacterial infections much harder to treat when you do have one.”
 
NPS MedicineWise is calling on all health professionals and consumers to pledge to fight antibiotic resistance at www.nps.org.au/join-the-fight or at www.facebook.com/NPSMedicineWise.