New Centre for Research in Paediatric Food Allergy and Food-related Immune Disorders

In response to the dramatic rise in allergies and public health concern, researchers and clinicians from across Australia have developed a collaborative research centre to tackle the growing allergy epidemic.
The Centre for Research Excellence in Paediatric Food Allergy and Food-related Immune Disorders, which is the only one of its kind in the world, was officially launched during World Allergy Awareness Week last week.
An alliance of leading researchers and centres in Australia will work together to focus on prevention. The team hopes to develop strategies to prevent food allergy developing, prevent adverse events in children with a food allergy and to prevent food allergy progressing to asthma.
Research by Murdoch Children’s, the University of Melbourne and the University of Western Australia has shown that food allergy and eczema may be the gateway disease. Infants with a food allergy are five times more likely to develop respiratory allergic diseases later in life.
Australia is leading the world in food allergy research. Already research from Murdoch Children’s and the University of Melbourne has found;

• The prevalence of food allergy in infants is 10 per cent, which was much higher than researchers anticipated.


• That early introduction of egg is safe and may even protect against the development of egg allergy - these results have underpinned the recently revised infant feeding guidelines.


• That pets, especially dogs, and having siblings may be protective factors for the development of food allergy.


• A novel two step testing approach to improve the precision of peanut allergy testing which will reduce the burden on overwhelmed allergy services.


• That Vitamin D status is integrally linked to the development of infantile food allergy.

Over the last ten years, there has been a five-fold increase in hospital admissions for life-threatening anaphylaxis. During the same period clinical referral for life-threatening peanut allergy of all ages has doubled in Australia. These changes are most pronounced in children less than five years, suggesting a causal role for early life determinants. These findings are reflected in unprecedented waiting lists for specialist allergists with most States of Australia reporting waiting lists in excess of 12 months.
In addition, there has been emerging concern over food immune disorders which also appear to be increasing in incidence. Of particular concern is coeliac disease, necessitating a gluten free diet, and Eosinophilic Esophagitis, where researchers say consensus management guidelines are urgently required.
The Centre has been funded by the National Health & Medical Research Council, and will provide evidence based guidelines that will inform public health policy and the clinical care of patients. These guidelines will support doctors, schools and community groups in the care of children with a food allergy.